Let's Talk About Joints 70. What about now? Nowadays, arthrosis
Joints provide the mobility of articulations has become a disease of very much younger
of the bones with each other and shock ab- people. This is a problem of modernity, stress,
sorption. They consist of the synovial mem- physical inactivity, preservatives in food and
brane (joint capsule), cartilaginous surfaces malnutrition in general. The joint must con-
(sliding between each other) and synovial stantly train, and with a sedentary lifestyle
fluid (the so-called lubricant). The structure it quickly degrades, since the cartilage is
of the cartilage contains cells (chondrocytes, nourished by passive diffusion of substanc-
chondroblasts), collagen, elastin, glycosami- es from the synovial fluid. On the contrary, it
noglycans. The cells occupy only 10% of the absorbs active substances and maintains its
volume and mass of the cartilage structure, properties with cyclic changes in shape and
everything else is the intercellular environ- structure (moderate loads).
ment. Cartilage nourishes through the ves- Factors accelerating aging and cartilage
sels of the bones and grows from the bone degradation:
outward (towards the sliding surface). The - obesity (increased stress on the joints);
cartilaginous surfaces are abraded despite - menopausal changes in the body (age-re-
the so-called lubrication and therefore must lated hormonal degradation of collagen);
regenerate thanks to the growth plate. Fric- - congenital and acquired connective tissue
tion products, in turn, enter the synovial fluid dysplasia (result of unnecessary vaccinations);
and are utilized by macrophages. What a wise - past diseases of the joints (trauma, arthri-
decision of nature, but there are nuances. tis, rheumatism);
The metabolism in cartilages is extremely - excessive occupational stress on the
slow, and the renewal cycle can reach several joints;
years. That is why, when patients with joint - metabolic disorders (hypertension, glyca-
problems visit us, we honestly tell them that tion affected by diabetes, hyperparathyroid-
the correction of the condition in arthrosis ism, hypothyroidism);
will take a long period. Furthermore, patients - hyperactive glycation (lifestyle, unhealthy
with arthrosis should be considered as pa- diet).
tients with a large number of concomitant When a joint is damaged, inflammatory me-
pathologies, since they have a “chronic in- diators are released into the synovial fluid,
flammation syndrome”. Such is the opinion which slow down the activity of chondro-
of many professional nutritionists convinced cytes by signaling (the same mediators are
of the relationship between atherosclerosis associated with atherosclerosis). But if the
and arthrosis, as “lying on the same patho- joint is damaged, it must be urgently restored,
genetic layer”. By the way, there is no such and chondrocytes, on the contrary, begin to
term as arthrosis in Europe. All joint pathol- release enzymes that dissolve the matrix of
ogies are arthritis. Hence the conclusion: the connective tissue. How can we accelerate the
presence of arthrosis significantly aggravates activity of chondrocytes and the regenera-
the course of other concomitant pathologies tion of the joints?
in the organism, due not only to similar bio-
chemical problems, but also to the accelerat- First, by suppressing the activity of cyto-ed degradation of the body during immobili- 1 kines and inflammatory prostaglandins,
zation. But this is a completely different story because inflammation is accompanied by
described in manuals on geriatrics… active hydrolysis of Type I collagen in the
An interesting fact — even 30–40 years body as a whole.
ago there was no arthrosis in people under This can be “seen” by the condition of
111 // Health territory. PEPTIDES. A Few Words on Joints
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