We can quite often hear the questions: «Can researchers of this topic actively promote the
we reverse the aging process? Can mankind use of antioxidants to prevent aging.
create an anti-aging pill?» Many people are Another theory of aging is associated with
concerned about these questions. Let us try the shortening of the end sections of chromo-
to consider them. somes — telomeres. At the ends of chromo-
The aging process is inherent, i.e. genetically somes there are protective blocks, or specific
determined. It can either proceed along the markers that show how many times the cell
physiological (normal) path, or follow an ac- can divide before its life cycle completes. In
celerated scenario. In such cases, we speak the event of a critical shortening of telomeres,
about aging or premature aging of the body. the cell is subject to disposal — this is how
Of course, today there are a lot of theories nature has programmed it. Thus, the longer
about how the functions of body organs and the ends of a chromosome, the longer the cell
systems are suppressed. And, of course, today can work, function and divide. With each cell
there are methods to slow down the aging division, the end portions of the chromosomes
process of the body, and bring its speed to are shortened, and when the number of divi-
normal physiological values. sions exceeds 46–47, the ends of the chromo-
On condition of timely intervention, doctors somes are practically bare. At this point, the
can delay the onset of the so-called «biological cell receives a signal that «it's time to retire».
autumn» in humans and prolong active old Among telomere theory advocates, there are
age, which means people can live an active those who propagate the use of activators of
and vibrant life at the age of 60, 70 or even the telomerase enzyme, a telomere builder.
80. This is the object of anti-aging medicine. Another aging theory is related to gene dis-
Currently, there is no universal pill, but there orders. It is believed that peptides are able to
is a wide range of medical tools that, when correct them. In other words, this is the pep-
applied together, can prolong youth. In par- tide theory of aging regulation developed in
ticular, there is an incredible amount of such our country. Its main provisions are based on
drugs in the Peptides product portfolio. In the fact that gene activity is associated with
order to understand how they work, let us the presence of a set of triggering signal mol-
have a closer look at the key aspects of body ecules called regulatory peptides. Over time,
aging processes. as well as under the influence of stresses and
There are many theories of aging. In the mental and physical overload, the number of
1950s, the American scientist Denham Har- regulatory peptides decreases. As a result, the
man proposed a free radical theory of aging. activity of the genetic apparatus and protein
It states that our own antioxidant systems reproduction reduce, too, and tissues begin
cannot cope with the volume of free radicals to malfunction.
(oxidants). As a result, cell walls and deoxyri- In addition to that, at times some cells may
bonucleic acid (DNA) molecules are damaged, fail altogether. The remaining active cells then
and it has dire consequences. Oxidation is dif- try to fulfill the function of an entire organ or
ficult to control; it can accelerate tissue degra- tissue as long as possible, and thus wear out.
dation, loss of cellular mass, accumulation of If we take into account that it may happen in
gene errors and mutations, which cannot be all systems of the body, we can speak about
easily fixed by the body's own repair systems. premature aging caused by peptide deficiency.
When the number of defective cells is exces- In the 70s-80s of the XX century, prototypes
sive, the immune system is not always able to of modern peptide bioregulators that correct
cope with them, i.e. track, destroy them and various body functions were developed in
maintain the inner balance. That is why many Russia.
7 // Health territory. PEPTIDES. Theories and Reasons of Aging
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