Pinealon
of pathological processes. The research results are presented in Table 5.
The influence of PINEALON® on the characteristics of the types of Table 5
electroencephalograms in patients with diseases of the central nervous system.
Group of patients examined EEG Type
III IV V
Before After Before After Before After
treatment treatment treatment treatment treatment treatment
After treatment with general purpose 6 (19%) 5 (16%) 11 (34%) 10 (31%) 10 (31%) 9 (28%)
drugs
After treatment using PINEALON® 9 (21%) 7 (17%) 14 (33%) 9 (21%) 13 (31%) 7 (17%)
Before treatment, pathological (III, IV, V) types of EEG prevailed in the examined patients in different
groups. Type III EEG was characterized by the presence of a so-called non-dominant curve at a low
amplitude level (no higher than 30-35 μV), the presence of irregular alpha activity, or even its absence.
The IV type of EEG was characterized by a highly emphasized regularity of rhythms, blurring of zonal
differences. The V type of EEG was characterized by irregular slow activity with an amplitude above
35 μV, sharp waves, and paroxysmal discharges.
The most pronounced changes in the brain’s bioelectric activity were observed in patients after treat-
ment with PINEALON®. First of all, this was confirmed on the EEG in a clearer modulation and res-
toration of zonal differences in the alpha rhythm, a weakening of the severity of irritative processes,
in some cases - the disappearance of paroxysmal discharges.
Effect of PINEALON® on the dynamics of changes in the alpha index in patients Table 6
with diseases of the central nervous system
Group of patients examined Alpha index
Before treatment After treatment
Healthy 51,7±3,2 -
Patients using general purpose drugs 36,2±3,4 43,2±4,5
Patients using Pinealon® 1669,1±56,3*# 46,1±4,5*#
* P <0.05 compared with the indicator in patients before treatment;
# P <0.05 compared with the indicator in patients after treatment with general purpose drugs.
In addition to visual EEG assessment, the alpha index was calculated in patients before and after treat-
ment (Table 6). It was found that there was a significant increase in the alpha index in patients of the
study groups under the influence of therapy. The value of the alpha index was significantly higher in
the group of patients after treatment with PINEALON® compared with the indicators in other groups.
However, the degree of change in the alpha index in patients receiving different treatments was not
the same.
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