Bonomarlot®
Biologically active food supplement BONOMARLOT® contains a complex of low molecular weight
peptides with a molecular weight of up to 5000 Da, extracted from bone marrow tissue of young
animals - calves not older than 12 months of age or pigs.
BONOMARLOT® is available in capsules with an active substance content of 10 mg.
BONOMARLOT® peptides regulate metabolic processes in the cells of the hematopoietic system,
increase its reserve capabilities, have a beneficial effect on the adaptation processes of the body in
extreme conditions, and have antioxidant properties regulating the processes of peroxidation in the
cells of the hematopoietic system. Experimental studies have shown that peptides have a tissue-
specific effect on the cells of those tissues from which they are isolated. This allows us to assume the
effectiveness of the use of BONOMARLOT® for restoring the functions of the hematopoietic system
in the case of its disorders of various origins, primarily in anemia.
Anemia is not an independent disease, but it occurs as a syndrome in a number of diseases that can
either be associated with a primary injury of the blood system or not depend on it. Therefore, anemia
is a widespread condition that requires targeted treatment, as the quality of life of people with anemia
is drastically reduced.
Any anemia leads to a decrease in the respiratory function of the blood and the development of oxygen
starvation of tissues, which is most often expressed by such symptoms as pallor of the skin, increased
fatigue, weakness, headaches, dizziness, rapid heartbeat, shortness of breath and others. A decrease
in hemoglobin concentration in the blood often occurs with a simultaneous reduction in the number
of red blood cells and their qualitative composition changes. In this case, it is essential to preserve
the ability of the bone marrow to regenerate, which is manifested by an increase in the number of
reticulocytes (young erythrocytes) in the peripheral blood (the norm is 0.5% -2%). Maintaining the
regenerative activity of the bone marrow helps to level the symptoms of anemia and improve the
patient’s general condition.
In general, the treatment tactics depend on the type of anemia and the severity of the patient’s
condition. Currently, vitamin B12 and iron supplements are mainly used to treat anemia. Also, with a
low hemoglobin level, red blood cell transfusions can be performed.
CLINICAL CHARACTERISTICS OF PATIENTS
A clinical study of the efficacy of BONOMARLOT® took place at the Medical Center of the Saint
Petersburg Institute of Bioregulation and Gerontology of the Northwest Branch of the Russian Academy
of Medical Sciences from April to November 2011.
The clinical study involved 26 women aged 35 to 56 years with signs of mild to moderate iron-
deficiency anemia due to malnutrition.
Patients complained of weakness, rapid fatigue, general malaise, decreased concentration, shortness
of breath after light or moderate physical activity, palpitations, headache, tinnitus, sleep, and appetite
disturbances.
An objective examination revealed pallor of the skin of visible mucous membranes and nail beds, as
well as the appearance of functional systolic murmurs in most patients.
During laboratory examinations, the patients showed a decrease in the hemoglobin content in the
blood to a level of 70-90 g/l, which indicates the presence of mild or moderate anemia.
All patients were divided into 2 groups. Patients in the control group (11 people) received conventional
therapy, including iron supplements, vitamin B12, and a special diet. In addition to conventional
treatment, patients of the primary group (15 people) received BONOMARLOT® 1 capsule 2 times a
day with meals for 30 days.
RESEARCH METHODS
We assessed the patients’ complaints and conducted general clinical blood tests during the study.
RESEARCH RESULTS
The use of BONOMARLOT® in patients with mild and moderate anemia improved the general condition,
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