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Брошюра «Клинические исследования пептидных биорегуляторов» Электронная версия на английском языке — страница 74

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Thyreogen® Influence of THYREOGEN® on the level of thyroid hormones in blood Table 1 serum in patients with primary hypothyroidism. Indicators Before Treatment After Treatment with Conventional After Treatment with Means Thyreogen® Т3, (nmol/l) 0,38±0,03 1,12±0,06 1,58±0,07* Т4, (nmol/l) 38,8±5,4 55,1±4,3 87,5±6,2* * P <0.05 - significant compared with the indicator in the control group patients. In the study of objective indicators, normalization of ECG parameters was observed. Attention is drawn to the fact that the indicators of the secretory function of the thyroid gland remained at the achieved level for 3-5 months after the course of treatment with the use of THYREOGEN®. The restoration of the level of thyroid hormones within the physiological norm was noted (Table 1), which indicates a stabilizing effect of the drug on the cellular metabolism of the gland and a regulatory effect on met- abolic processes. Thus, the obtained results of a clinical study of the drug indicate the effectiveness and appropriate- ness of the use of THYREOGEN® in the complex treatment and prevention of thyroid dysfunctions of various origins. Clinical study of THYREOGEN® revealed no side effects or contraindications. The drug does not cause complications or drug dependence. The studied ready-made form of THYREOGEN® is convenient for inpatient, outpatient, and at-home use. THYREOGEN® can be used for therapeutic and prophylactic purposes in the form of a biologically active food supplement as an adjuvant in combination with any means of symptomatic and patho- genetic therapy used to treat diseases caused by dysfunction of the thyroid gland of various origins. CONCLUSION The biologically active food supplement THYREOGEN® has a normalizing effect on the metabolism of thyroid cells. THYREOGEN® is well tolerated by patients when taken orally, has no side effects, has no contraindi- cations, and can be used as a therapeutic and prophylactic biologically active food supplement. REFERENCES 1. Belousov Y.B., Moiseev V.S., Lepakhin V.K. Clinical Pharmacology and Pharmacotherapy: A Guide for Physicians. - M.: the Universe, 1993. -- 398 p. 2. Mashkovsky M.D., Medicines: Pharmacotherapy for doctors, manual: 2 parts. – Vilnius: ZAO “Gam- ta”, 1993. 3. Geriatric manual / Ed. D.F. Chebotarev, N.B. Mankovsky. – M.: Medicine, 1982. – 544 p. 4. Tepperman J., Tepperman H. Physiology of metabolism and the endocrine system: Translation from English - M.: Mir, 1989. -- 656 p.

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