Chelohart®
Dynamics of changes in the indicators of mineral metabolism in the blood of Table 2
patients with coronary heart disease.
Indicator Norm Patients Treated with Conventional Patients who additionally received
Means Chelohart®
Before After Treatment Before After Treatment
Treatment Treatment
Potassium, mmol/l 3,4-5,3 3,13±0,6 3,48±0,4 3,10±0,4 3,52±0,5
Calcium, mmol/l 2,3-2,75 2,22±0,03 2,36±0,06 2,23±0,05 2,41±0,06
Magnesium, mmol/l 0,7-1,2 0,83±0,04 0,88±0,06 0,84±0,07 0,90±0,05
According to veloergometry data, the appearance of an attack of angina pectoris at the height of activity
after using CHELOHART® was observed reliably 1.9 times less often than before treatment, while in
patients of the control group - only 1.4 times (Table 3). After complex treatment with CHELOHART®,
54.5% of patients achieved a submaximal heart rate (HR) at the height of the threshold activity, while
in the control group - only 40% (before treatment - 21.9% of patients in both groups).
The tolerance assessment was carried out according to the threshold power value and the total amount
of work performed. As an indicator of positive antianginal treatment, tolerance to physical activity
was significantly higher in patients of the primary group after taking CHELOHART® compared with
indicators before treatment. However, the difference with indicators in patients in the control group
was insignificant.
To assess the efficiency of the cardiovascular system, the energy expenditure index was calculated.
A 1.6-fold decrease in the index after using CHELOHART® testified to a more economical expendi-
ture of energy reserves of the heart due to a decrease in myocardial oxygen demand during work (in
patients of the control group - by a factor of 1.3), which was reflected in a significant increase in the
index of maximum oxygen consumption by 16% in patients of the primary group (in the control group
- by 11%) compared with the indicator before treatment.
Dynamics of veloergometry indicators in patients with ischemic heart Table 3
disease.
Indicator Before Treatment After Treatment with After Treatment with
Conventional Means Chelohart®
The frequency of angina attacks,% 68,8 50* 36,4*#
Achievement of submaximal heart rate,%
21,9 40* 54,5 *#
Veloergometry threshold power, W/min 96,9±4,6 115,2±5,4 119,3±4,6*
Total work, kgm 2830±118 3457±110* 3673±119*
Energy cost index, units 15,8±1,4 11,9±2,4* 9,6±2,1*
Maximum oxygen consumption index, units 1,3±0,03 1,44±0,05* 1,49±0,04*
* p <0.05 compared with the indicator in patients before treatment;
# p <0.05 compared with the indicator in patients after treatment with conventional means.
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