Endoluten®
Biologically active food supplement ENDOLUTEN®contains a complex of low molecular weight pep-
tides with a molecular weight of up to 5000 Da, isolated from the pineal gland tissues of young ani-
mals - calves up to 12 months age or pigs.
ENDOLUTEN® is available in capsules with an active substance content of 10 mg.
ENDOLUTEN®’s peptides regulate metabolic processes in neuroendocrine cells of various tissues, in-
cluding the pineal gland, increasing the neuroendocrine system’s reserve capacity, having a beneficial
effect on the adaptation processes of the body in extreme conditions, and have antioxidant proper-
ties, which regulate the processes of peroxidation in various tissues. Experimental studies have shown
that peptides have a tissue-specific effect on the cells of those tissues from which they are isolated.
This allows us to assume the effectiveness of the use of ENDOLUTEN® for the restoration of neuro-
endocrine regulation in case of disorders of various origins.
According to experimental data, ENDOLUTEN® contributes to the normalization of neuroendocrine
regulation of the body’s main functions.
It is known that the age-related decrease in the functional activity of the pineal gland causes a dis-
turbance of the mechanisms of interaction of the nervous, endocrine, and immune systems and con-
tributes to the development of various diseases and pathological conditions. The impact of extreme
environmental, climatic-geographical, professional, and psycho-emotional factors on the human body
leads to neuroendocrine and immunological disorders that cause maladjustment disorders and psy-
chosomatic diseases (3, 4, 5, 6).
The medical treatment of these diseases and pathological conditions includes the use of a wide vari-
ety of drugs, depending on the symptoms of the disease. However, the correction of these disorders
is based on the prescription of certain medications (1, 2):
- Adaptogens (ginseng, extracts of Eleutherococcus, Leuzea, Rhodiolarosea, tinctures of aralia, zamani-
hi, saparal, pantocrine);
- Peptide immunomodulators (thymalin, taktivin, thymogen, myelopid);
- Pineal gland hormone - melatonin;
- Pineal gland peptides - epithalamin;
- Multivitamins;
- etc.
However, drugs have side effects and cannot be prescribed to prevent the listed pathological condi-
tions. In this regard, developing new effective and safe means for prevention and increasing the ef-
fectiveness of treating patients with pathological conditions associated with impaired neuroendocrine
regulation is an urgent problem.
Clinical trials of ENDOLUTEN® were carried out in 163 patients (including 48 men, 115 women)
with dyshormonal myocardial dystrophy, physiogenic asthenia, and climacteric syndrome of mild and
moderate severity in women, as well as in cancer patients after courses of radiation and chemother-
apy, treated at the St. Petersburg Medical Center of the Institute of Bioregulation and Gerontology,
SZO RAMS from January to August 2011. The distribution of patients by nosological forms, sex, and
age is presented in Table 1.
Для таблиц, дозировок и примечаний сверяйтесь с оригинальным PDF: при извлечении текста порядок колонок может измениться.
Из библиотеки Peptides. Авторство и содержание оригинала сохранены. Размещено с разрешения поставщика.