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Брошюра «Тезисы докладов компании Peptides на международных конгрессах» на английском языке — страница 17

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We measured: • indicators of the thyroid hormones levels; • indicators of the antibodies levels; • indicators of high-reliability infrared thermography (detects the most earlier changes in organs up to 0.01 degree Celsius); • indicators of ultrasonography of the thyroid gland. Results The study showed that applying a complex of peptide medications to treat patients with autoimmune thyroiditis in the 2nd and 3rd groups helped improve general health. Laboratory and instrumental indicators also improved. The most positive dynamics were observed in the 3rd group, treated with a complex of two peptide drugs. Considering the results of our study, we can say that our complex of thyroid gland peptides has a regulatory effect on hormonal function but does not affect antibody levels. However, a complex of peptide drugs aimed at different parts of the pathogenesis of autoimmune thyroiditis (Thyreogen, Endoluten) had a more pronounced effect than just taking Thyreogen. This complex also caused an antibody level reduction and the positive changes in the thyroid gland, detected by ultrasonography. Efficiency of a complex of peptides (Endoluten and Thyreogen) in case Table 1 of autoimmune thyroiditis Indicators Norm Before Group 1 Group 2 Group 3 treatment Standard Standard Standard treatment and treatment treatment and Thyreogen, Endoluten Thyreogen Number of 218 89 42 87 patients USG - - - - + * IRTG - - - + * + * T4 (Nmol/l) 0.8-2.1 0.85±0.16 0.92±0.11 0.98±0.06 1.16±0.06 * TSH (mIU/l) 0.35-4.5 8.84±1.09 7.14±0.86 4.09±0.12 * 3.94±0.12 * ATG (IU/l) 0-4.1 87.1±7.14 83.32±3.28 77.41±1.18 * 18.91±1.65 * ATPO (IU/l) 0-5.61 371.2±22.6 361.24±12.4 357.23±11.41 29.16±2.54 * — reliable, compared with the group 1; + — positive changes; USG — ultrasonography; IRTG — infrared thermography; ATG — anti-thyroglobulin autoantibodies; ATPO — anti-thyroid peroxidase autoantibodies. Dublin, Ireland 2015 San Francisco, USA 2017

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