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Брошюра «Тезисы докладов компании Peptides на международных конгрессах» на английском языке — страница 22

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Results It was revealed that applying a complex of peptide medications in treating patients with fast ovarian aging in the 2nd group helped improve general health. Laboratory and instrumental indicators also improved. Considering the results of our study, we can say that our complex of peptides has a regulatory effect on hormonal function and ovarian functional reserve. This complex also caused the positive changes in ovaries, detected by ultrasonography. Efficiency of a complex of peptides (Endoluten and Zhenoluten) in case Table 1 of fast ovarian aging Indicators Follicular Norm Group 1 Before Group 1 Placebo Group 2 Before Group 2 Peptides phase treatment 4 months later treatment 4 months later Number of patients 62 62 214 214 USG 10-25 follicles 7-8 / 7-8 8-9 / 7-8 7-8 / 7-8 + * Increase in the for each ovary 11-12 / 10-11 number of antral (98 % cases) follicles (left / right) FSH 1.4-9.9 mIU/lv 6.38±0.42 5.71±0.29 6.24±0.31 4.96±0.29 Estradiol 68-1269 183.14±16.92 209.26±12.64 194.16±11.57 616.24±69.42 * pmoI/l AMH 1.00-12.6 0.74±0.12 0.82±0.24 0.76±0.13 1.16±0.18 * ng/ml (68 % cases) Onset No data - 8 % - 71 % of pregnancy * — reliable, compared with the group 1; + — positive changes; USG — ultrasonography; FSH — follicle-stimulating hor­ mone; AMH — anti-Mullerian hormone. Comparative analysis of the application of peptide medications in case of fast ovarian aging shows that it is preferable to apply this complex of peptides containing ovarian and pineal gland peptides as a pregnan­ cy medication program and as a part of a complex treatment instead of hormonal therapy. These drugs have no side effects, do not cause complications or addiction. There are no medical contraindications to their use. We also recommend this complex to maintain the neuroendocrine and reproductive system functions to prevent metabolic disorders in middle and senior age. Recommended dosages: Zhenoluten — 2 capsules per day for 4 months. Endoluten — 1 capsule per day (in the morning) for 4 months. It is advisable to repeat courses of treatment every 6 months. Conclusion Based on the data obtained during the study, we can conclude that existing conventional treatment reg­ imens of fast ovarian aging require revision and a new approach. The new method involves the inclusion of these high-performance schemes, which use physiological peptide drugs with targeted action aimed at increasing the reserve capacity of the organs and tissues involved in the pathological processes. Gothenburg, Sweden 2019

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